Cytori Therapeutics Inc (NASDAQ:CYTX) has presented preclinical data that demonstrates thermal burn healing abilities of the Cytori Cell Therapy. The demonstration reveals how the therapy can promote the healing of the burn wound using topical spray delivery. The effect of topical administration of the therapy is almost similar to that of a local injection.
The study performed with support from the BARDA has been published through a paper named “Adipose-Derived Regenerative Cell Therapy for Burn Wound Healing: A comparison of two delivery methods.”
Topical Spray can Optimize Burn Care
According to UCSD Burn Center plastic surgeon, Dr. Mayer Tenehaus, the data reveal that the topical spray offers a better option of using Cytori Cell Therapy. Contrarily, it is helpful in potentially optimizing the standard of care in fragile burn patients.
The study was carried out to compare the effectiveness of topical spray delivery against the injection of Cytori Cell Therapy. A porcine model was used to analyze the effectiveness of both the sources of drug administration.
Principal findings of the data include significant improvement over the control in epithelialization, inflammatory cell infiltration and blood vessel density on the administration of the topical spray. Since the results of the topical spray were found to be equivalent to the local injection, it has been concluded that the spray delivery mechanism is a better and viable option.
Statistical Findings of the Study
The research is to be submitted to the FDA and is going to be included in the Investigational Device Exemption (IDE) package for the proposed use of Cytori Cell Therapy for treating thermal burn injury.
The study results have revealed that when local injection or topical spray of Cytori Cell Therapy was administered on the burn wound, its healing capacity increased by around 21%. Moreover, when a digital analysis was carried out of the wound post seven days of treatment, the microvessel density in wounds treated with the Cytori Cell Therapy were significantly more.
Therefore, the Cytori Cell Therapy is being considered an attractive alternative to optimize skin healing due to thermal burn and can also be used effectively as an adjunct therapy to skin grafting in patients with multiple wounds.